Future cyber-physical systems are expected to be adaptable in the field without sacrificing dependable operation. This project looks into ways to enable the rapid deployment of new software variants without inducing safety risks. In this context, we address challenges related to interactions with the technical environment the system is placed in. This echoes new legal requirements regarding remote human oversight for autonomous driving and also the availability of edge cloud services for extended functionality or for the continuous certification of new software variants. Project C3 will address these challenges by novel combinations of techniques from runtime monitoring and from confidential computing, together with advanced safeguarding mechanisms.